Symptoms

Lipodystrophy has a core characteristic of complete or partial loss of adipose tissue.1 In inherited forms, characteristic signs and symptoms can be apparent either from birth or early childhood in congenital generalised lipodystrophy (CGL) or can occur when patients approach puberty in familial partial lipodystrophy (FPLD).1,2 In acquired forms, signs and symptoms can develop anytime in life, more commonly first detected in childhood or early adulthood.

Medical professionals can use these diagnostic aids:

Here are two leaflets that can held you diagnose patients
with GL or PL.

Download the diagnose leaflet
for Generalised lipodystrophy (GL)

Download the diagnose leaflet
for Partial lipodystrophy (PL)

References

  1. Garg A. Clinical review#: Lipodystrophies: genetic and acquired body fat disorders. J Clin Endocrinol Metab. 2011;96(11):3313-3325.

  2. Akinci B, Meral R, Oral EA. Phenotypic and Genetic Characteristics of Lipodystrophy: Pathophysiology, Metabolic Abnormalities, and Comorbidities. Curr Diab Rep. 2018;18(12):143. Published 2018 Nov 8.